Our Pipeline
Medical Research
In order to start clinical trials with its treatment, AlphaOnco carries out research in the following areas:
Results
Optimization of the growth of magnetotactic bacteria
This result was obtained in partnership with UPMC.
Study of magnetosomes directly extracted from magnetotactic bacteria
In early antitumor efficacy studies, AlphaOnco researchers used suspensions containing magnetosome chains directly extracted from magnetotactic bacteria. To prepare these suspensions, we did not specifically treat the magnetosome chains, and they were therefore surrounded by biological material (lipids, proteins, endotoxins) originating from magnetotactic bacteria.
Study of coated magnetosome minerals
To avoid the toxicity problems related to the presence of endotoxins and immunogenic organic substances at the surface of magnetosome minerals, Nanobacterie researchers have developed a four-stage synthesis method:
Probe based on fluorescent magnetosomes
AlphaOnco has developed a method for producing fluorescent magnetosomes that can be used as fluorescent probes. To do this, 400 μM of rhodamine B is introduced to the culture medium of magnetotactic bacteria.
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