Publications
List of publications:
Magnetosome heating mechanisms by applying an oscillating field
Heat Production by Bacterial Magnetosomes Exposed to an Oscillating Magnetic Field, E. Alphandéry, S. Faure, L. Reason, E. Duguet, P.A. Howse, and D.A. Bazylinski, Journal of Physical Chemistry C, Vol. 115, p. 18-22 (2011).
Doping magnetosomes with cobalt to improve their heating properties
Chains of Cobalt Doped Magnetosomes Extracted from AMB-1 Magnetotactic Bacteria for Application in AMF Hyperthermia, E. Alphandery, Carvallo C., Menguy N., Chebbi I., Journal of Physical Chemistry C, Vol. 115, p. 11920-11924 (2011).
Mechanism of stimulation of bacterial production by addition of chelating additive
The effect of iron-chelating agents on Magnetospirillum magneticum strain AMB-1: stimulated growth and magnetosome production and improved magnetosome heating properties, E. Alphandéry, M. Amor, F. Guyot & I. Chebbi, Applied Microbiology and Biotechnology, Vol. 96, 663-670 (2012).
Chains of Magnetosomes Extracted from AMB-1 Magnetotactic Bacteria for Application in Alternative Magnetic Field Cancer Therapy, E. Alphandéry, S. Faure, O. Seksek, F. Guyot, and I. Chebbi, ACSNano, Vol. 5, p. 6279-6296 (2011).
Use of magnetosomes as a magnetic detection probe
Abstract: A new technology for multiparametric detection, E. Alphandérya, L. Lijeour, Y. Lalatonne, L. Motte, Sensors and Actuators B: Chemical, Vol. 147, p. 786-790 (2010).
Review on the development of different nano-drugs
Cancer Therapy Using Nanoformed Substances: Scientific, Regulatory and Financial Aspects, E. Alphandéry, P. Grand-Dewyse, R. Le Fevre, C. Mandawala, M. Durand-Dubief, Expert Review of Anticancer Therapy, Vol 15, P. 1233 -1255 (2015).
Preparation and properties of coated pyrogen-free magnetosome minerals
Biocompatible and stable magnetosome minerals coated with poly-L-lysine, citric acid, oleic acid, and carboxy-methyl-dextran for application in the magnetic hyperthermia treatment of tumors, C. Mandawala, I. Chebbi, M. Durand-Dubief, R Le Fevre, Y. Hamdous, F. Guyot, E. Alphandery, Journals of Materials Chemistry B, Vol. 5, p. 7644-7660 (2017).
Biocompatible coated magnetosome minerals with various organism and cellular interaction properties induce cytotoxicity towards RG-2 and GL-261 glioma cells in the presence of an alternating magnetic field, Y. Hamdous, I. Chebbi, Ch. Mandawala, R. Le Fevre, F Guyot, O. Seksek, and E. Alphandéry, Journal of Nanobiotechnology, V. 15:74 (2017).
Treatment of intracranial U87-Luc glioblastomas
Chains of magnetosomes with controlled endotoxin release and partial tumor induce full destruction of intracranial U87-Luc glioma in mice under the application of an alternating magnetic field, E. Alphandéry, A. Idbaih, C. Adam, J-Y. Delattre, C. Schmitt, F. Guyot, I. Chebbi, Journal of Controlled Release, V. 262, P. 259-272 (2017).
The development of non-pyrogenic magnesium oxide coated with poly-l-lysine in U87-Luc glioblastoma in 100% of treated mice using magnetic hyperthermia, E. Alphandéry, A. Idbaih, C. Adam, J-Y. Delattre, C. Schmitt, F. Guyot, I. Chebbi, Biomaterials, V. 141, P. 210-222 (2017).
Treatment of subcutaneous glioblastoma GL-261
Enhanced antitumor efficacy of biocompatible magnetosomes for the magnetic hyperthermia treatment of glioblastoma, Raphael Le Fevre, Mickael Durand-Dubief, Imene Chebbi, Chalani Mandawala, Lagroix France, Jean-Pierre Valet, Ahmed Idbaih, Adam Clovis, Jean-Yves Delattre, Charlotte Schmitt , Caroline Maake, François Guyot, Edouard Alphandéry, Theranostics, V. 7, P. 4618-4631 (2017).
Development of a nanometric fluorescent probe for temperature detection
A Nanoprobe Synthesized by Magnetotactic Bacteria, Detecting Fluorescence Variations under Dissociation of Rhodamine B from Magnetosomes Following Temperature, pH Changes, or the Application of Radiations. Edouard Alphandery, Darine Abi-Haidar, Olivier Seksek, Maxime Thoreau, Alain Trautmann, Nadege Bercovici, Florence Gazeau, Francois Guyot, Imene Chebbi. ACS applied materials and interfaces. DOI: 10.1021 / acsami.7b09720 (2017)
Review on medical use of Magnetosomes
Use of bacterial magnetosomes in the magnetic hyperthermia treatment of tumors: A review. Edouard Alphandéry, Imène Chebbi, Francois Guyot, Mickael Durand-Dubief. International Journal of Hyperthermia, V. 29, P. 801-809 (2013).
Iron isotopes in magnetosomes
Mass-dependent and -independent signature of Fe isotopes in magnetotactic bacteria. Matthieu Amor, Vincent Busigny, Pascale Louvat, Alexandre Gélabert, Pierre Cartigny, Mickael Durand-Dubief, Georges Ona-Nguema, Edouard Alphandéry, Imène Chebbi, François Guyot. Science. Flight. 352, P.705-708 (2016).
Chemical signature of magnetotactic bacteria. Matthieu Amor, Vincent Busigny, Mickael Durand-Dubief, Georges Ona-Nguema, Alexandre Gélabert, Edouard Alphandéry, Nicolas Menguy, Marc Benedeti, Imène Chebbi, François Guyot. Proceedings of the National Academy of Science. V. 112, p. 1699-1703 (2015).
Review on therapies used for the treatment of glioblastoma
Glioblastoma Treatments: An Account of Recent Industrial Developments. Edouard Alphandéry. Frontiers in Pharmacology. V 13; 9:879 (2018).
Use of fluorescent magnetosomes for drug release
Fluorescent magnetosomes for controlled and repetitive drug release under the application of an alternating magnetic field under conditions of limited temperature increase (<2.5 °C). Edouard Alphandéry, Darine Abi Haidar, Olivier Seksek, François Guyot, Imène Chebbi. Nanoscale. Vol 14; 10(23): 10918-10933 (2018).
Iron isotope study for the biomineralization of magnetite in bacteria
Iron uptake and magnetite biomineralization in the magnetotactic bacterium Magnetospirillum magneticum strain AMB-1: An iron isotope study. Matthieu Amora, Vincent Busigny, Pascale Louvat, Mickaël Tharaud, Alexandre Gélabert, Pierre Cartigny, Julie Carlut, Aude Isambert, Mickaël Durand-Dubief, Georges Ona-Nguema, Edouard Alphandéry, Imène Chebbi, François Guyot. Geochimica et Cosmochimica Acta Volume 232, Pages 225-243 (2018).
Mechanisms of magnetosomes chains orientation in magnetotactic bacteria
Magnetic-field induced rotation of magnetosome chains in silicified magnetotactic bacteria. Marine Blondeau, Yohan Guyodo, François Guyot, Christophe Gatel, Nicolas Menguy, Imène Chebbi, Bernard Haye, Mickaël Durand-Dubief, Edouard Alphandery, Roberta Brayner, Thibaud Coradin. Scientific Reports. Vol 16;8(1):7699 (2018).
Treatment of intracranial U87-Luc glioblastomas
Biodegraded magnetosomes with reduced size and heating power maintain a persistent activity against intracranial U87‑Luc mouse GBM tumors. . V 17:126 (2019).
Review on iron oxide nanoparticles as imaging tool
Iron oxide nanoparticles as multimodal imaging tools.
Review on biodistribution and targeting properties of iron oxide nanoparticles for the treatment of cancer and iron anemia
Biodistribution and targeting properties of iron oxide nanoparticles for treatments of cancer and iron anemia disease.
Review on nanomedecine regulations
A discussion on existing nanomedicine regulation: Progress and pitfalls. Applied Materials Today. Vol 17 193–205 (2019).
Review on the therapeutic use of iron oxide nanoparticles
Iron oxide nanoparticles for therapeutic applications. Drug Discovery Today. Volume 25, Issue 1, Pages 141-149 (2020).
Review on the therapeutic use of nanotechnology for the treatment and the diagnostic of coronavirus
The Potential of Various Nanotechnologies for Coronavirus Diagnosis/Treatment Highlighted through a Literature Analysis. Bioconjugate Chem. Vol 31, 1873−1882 (2020).
Review on the therapeutic use of biomineralized iron oxide nanoparticles for the treatment of cancer
Bio-synthesized iron oxide nanoparticles for cancer treatment. International Journal of Pharmaceutics. Vol 586 119472 (2020).
Review on the therapeutic use of metallic nanoparticles in oncology
Natural Metallic Nanoparticles for Application in Nano-Oncology. Edouard Alphandéry. Int J Mol Sci. Vol 21(12): 4412 (2020).
Review on the therapeutic use of magnetotactic bacteria and magnetosomes for cancer treatment
Applications of magnetotactic bacteria and magnetosome for cancer treatment: A review emphasizing on practical and mechanistic aspects. Edouard Alphandéry. Drug Discovery Today. Vol 25, NO 8 (2020).
Review on therapeutic use of nanotechnology for the treatment of glioblastoma
Nano-Therapies for Glioblastoma Treatment. Edouard Alphandéry. Cancers (Basel). Vol 12(1): 242 (2020).
Production of magnetosomes by the bacterial strain MSR-1 in a minimal growth media
A Method for Producing Highly Pure Magnetosomes in Large Quantity for Medical Applications Using Magnetospirillum gryphiswaldense MSR-1 Magnetotactic Bacteria Amplified in Minimal Growth Media. Clément Berny, Raphael Le Fèvre, François Guyot, Karine Blondeau, Christine Guizonne, Emilie Rousseau, Nicolas Bayan and Edouard Alphandéry. Front Bioeng Biotechnol. Vol 8: 16 (2020).
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